Evidence of heterokaryon compatibility on Candida albicans biofilm

Gustavo Alberto Obando-Pereda, Paula Cristina Anibal, Vivian Fernandes Furletti, José Francisco Hofling

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

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Aims: Candida species, especially Candida albicans, are frequently found associated with biomaterials and immunosuppressed patients, and have been described as the most virulent yeasts in human fungi diseases. These yeasts have recently been isolated from periodontal pockets, revealing the penetration of hyphae into the periodontal connective tissue. Methods: In this study, 7 periodontal C. albicans strains were applied individually in biofilm development on titanium discs and the samples were thereafter analyzed as for the number of colony forming units per milliliter (CFU/mL), dry-weight and scanning electron microscopy (SEM). Results: Counting of CFU/mL and determination of dry-weight showed that all samples formed biofilm. SEM analysis showed the development of a polymorphic network in the biofilms and the presence of hyphal anastomosis in the sites where fusion between the hyphae occurred. Conclusion: periodontal C. albicans strains present heterokaryon compatibility.

Idioma originalInglés
Páginas (desde-hasta)1678-1681
Número de páginas4
PublicaciónBrazilian Journal of Oral Sciences
EstadoPublicada - 2008
Publicado de forma externa


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