TY - GEN
T1 - Development and validation of a voltammetric method for quantifying lead in rat blood
AU - Roberto Irias Zelaya, Calos
AU - Fernanda Madrid Mendoza, Maria
AU - María Villanueva Salas, Ana
AU - Rojas Tamata, Karen
AU - Carpio Carpio, José M.
AU - Villanueva Salas, José A.
AU - Choquenaira-Quispe, Celia
N1 - Publisher Copyright:
© 2024 Latin American and Caribbean Consortium of Engineering Institutions. All rights reserved.
PY - 2024
Y1 - 2024
N2 - Lead is a toxic heavy metal that does not have any biochemical or physiological role. On the contrary, it produces multisystemic alterations that could lead to the death of a living being. Although there are standardized methods for lead quantification, electroanalytical techniques are presented as a rapid, sensitive, and economical alternative. In this investigation, we developed and validated a voltammetric method for quantifying lead in blood. The voltammetric method was used to quantify lead in rat blood. The results showed a linear relationship with a determination coefficient (R2) greater than 0.999. The method was precise with variation coefficients lower than 2.7% and accurate with recovery percentages close to 100%. The limits of detection and quantification were 0.000134 and 0.001433 mg/L, respectively. The obtained results propose an optimized alternative method for quantifying lead in blood with reliable results quickly.
AB - Lead is a toxic heavy metal that does not have any biochemical or physiological role. On the contrary, it produces multisystemic alterations that could lead to the death of a living being. Although there are standardized methods for lead quantification, electroanalytical techniques are presented as a rapid, sensitive, and economical alternative. In this investigation, we developed and validated a voltammetric method for quantifying lead in blood. The voltammetric method was used to quantify lead in rat blood. The results showed a linear relationship with a determination coefficient (R2) greater than 0.999. The method was precise with variation coefficients lower than 2.7% and accurate with recovery percentages close to 100%. The limits of detection and quantification were 0.000134 and 0.001433 mg/L, respectively. The obtained results propose an optimized alternative method for quantifying lead in blood with reliable results quickly.
KW - blood
KW - heavy metal
KW - Lead
KW - validation
KW - voltammetry
UR - http://www.scopus.com/inward/record.url?scp=85203792963&partnerID=8YFLogxK
U2 - 10.18687/LACCEI2024.1.1.1127
DO - 10.18687/LACCEI2024.1.1.1127
M3 - Conference contribution
AN - SCOPUS:85203792963
T3 - Proceedings of the LACCEI international Multi-conference for Engineering, Education and Technology
BT - Proceedings of the 22nd LACCEI International Multi-Conference for Engineering, Education and Technology
PB - Latin American and Caribbean Consortium of Engineering Institutions
T2 - 22nd LACCEI International Multi-Conference for Engineering, Education and Technology, LACCEI 2024
Y2 - 17 July 2024 through 19 July 2024
ER -