Bioactive compounds of loquat (Eriobotrya japonica lindl.) cv. golden nugget and analysis of in vitro functionality for hyperglycemia management

Título traducido de la contribución: Compuestos bioactivos de níspero (Eriobotrya japonica lindl.) cv. golden nugget y análisis de su funcionalidad in vitro para el manejo de la hiperglicemia

Jaime Ahumada, Claudia Fuentealba, José A. Olaeta, Pedro Undurraga, Romina Pedreschi, Kalidas Shetty, Rosana Chirinos, David Campos, Lena Gálvez Ranilla

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

16 Citas (Scopus)

Resumen

The loquat cultivar Golden Nugget (leaves, flowers and fruits), which has potential commercial importance in Chile, was analyzed for targeted bioactive composition (total phenolic contents: TPC, phenolic profiles and triterpenic acids) and in vitro bioactivity such as antioxidant capacity (AC) and inhibitory activity against enzymes relevant for hyperglycemia (α-amylase and α-glucosidase) and hypertension (angiotensin I-converting enzyme, ACE-I) management. Leaves and flowers had higher TPC and AC than fruits and hydroxycinnamic acid derivatives were found in all structures by HPLC. Chlorogenic acid and quercetin derivatives were detected only in leaves and flowers, which also inhibited the α-amylase and α-glucosidase enzymes, but flowers showed the highest anti-hyperglycemia activity. No inhibition of ACE-I and hyperglycemia-relevant enzymes were found in loquat fruits; additionally, TPC and AC were high at the green stage. Loquat leaves and flowers are sources of phenolic bioactives with potential for diet-based hyperglycemia management. No triterpenic acids were found in any of the loquat parts.

Título traducido de la contribuciónCompuestos bioactivos de níspero (Eriobotrya japonica lindl.) cv. golden nugget y análisis de su funcionalidad in vitro para el manejo de la hiperglicemia
Idioma originalInglés
Páginas (desde-hasta)272-284
Número de páginas13
PublicaciónCiencia e Investigacion Agraria
Volumen44
N.º3
DOI
EstadoPublicada - dic. 2017
Publicado de forma externa

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